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Evidence-based insights from 20+ clinical trials across multiple ethnicities.
Clinical Evidence
The Eyerising Myopia Management Device and RLRL therapy have been the subject of multiple published clinical and real-world studies conducted internationally. These studies have explored the safety and efficacy of RLRL therapy as an intervention for managing childhood myopia, involving diverse paediatric populations and research settings across different ethnicities.
Up to 87.7% reduction in axial elongation reported in clinical studies, representing one of the highest efficacy outcomes documented among approved myopia management interventions.1
Clinical trials have been conducted across multi-ethnic cohorts spanning Asia, Europe, and Australia, providing evidence for treatment efficacy across diverse patient populations.
Evidence encompasses both standalone RLRL therapy trials and adjunctive therapy trials in combination with orthokeratology, soft contact lenses, and spectacle lenses.
Long-term follow-up data of up to 5 years is available, providing a safety and efficacy evidence base unique among myopia management modalities.
1 Jiang Y, Zhu Z, Tan X, Kong X, Zhong H, Zhang J, Xiong R, Yuan Y, Zeng J, Morgan IG, He M. Effect of repeated low-level red-light therapy for myopia control in children: a multicenter randomized controlled trial. Ophthalmology. 2022;129(5):509-19.
Research Programs
The Eyerising clinical evidence base spans a range of study designs, reflecting the rigor expected of an approved medical device.
Randomised Controlled Trials
Pivotal RCTs with sham-controlled or active-comparator designs, providing the highest level of clinical evidence for the efficacy and safety of RLRL therapy in paediatric myopia management.
Real-World Evidence Studies
Prospective real-world evidence studies capturing treatment outcomes across diverse clinical settings, patient demographics, and co-prescribed interventions. Data includes tens of thousands of patients across 40+ countries.
Combination Therapy Trials
Trials investigating RLRL in combination with other established myopia management modalities:
- RLRL + Orthokeratology
- RLRL + Soft Multifocal Contact Lenses
- RLRL + Myopia Control Spectacle Lenses
Long-Term Safety and Efficacy Monitoring
Extended follow-up programs tracking ocular structural integrity, visual function, and sustained efficacy at up to 5-year time points. Post-market surveillance programs complement controlled trial data with continuous safety monitoring.
Research Collaborations
Ongoing investigations are being conducted in collaboration with academic and clinical partners across Asia, Europe, and Australia, including trials assessing RLRL as both a standalone and adjunctive therapy. Peer-reviewed publications to date have reported favourable trends in slowing myopia progression and maintaining visual outcomes within established safety parameters.
All research is carried out under appropriate ethics approvals and in accordance with recognised international standards for medical device evaluation.
Access Clinical Resources
For key publications, paper summarises and updates on emerging data, please contact us on info@eyerisinginternational.com.